Food intolerance comprises the major part of the adverse reactions which individuals have to food and affects our health in numerous ways.
Multiple clinical manifestations of food intolerance include gastrointestinal (GI) disorders along with various diseases of other organ systems:
The most important function of the GI tract is to digest the food intake and adsorb nutrients. Chronic stimulation of the GI tract with certain food ingredients (food antigens) can impair basic functions and potentially lead to chronic inflammation and greater permeability of the gut mucosa, phenomenon also recognized as “leaky gut syndrome”.
lactose-or fructose intolerance, histamin intolerance
If the gut permeability is increased, undigested food ingredients leak through the intestines into the bloodstream. The body then recognizes these particles as foreign “invaders,” and the immune system attempts to fight them off, causing various autoimmune disorders.
Numerous studies describe the role of IgG involvement in food intolerance nature. Specific serum IgG / IgG4 antibodies have been reported in cases of celiac disease, dermatitis or atopic eczema, as well as in disease with increased intestinal permeability and IBS.
The role of food in IBS requires specific mention. Majority of patients with IBS connect their symptomsto certain foods:
With a delayed food hypersensitivity, the symptom does not occur until hours or even days after the triggering food has been consumed. Due to this delayed reaction, it is often impossible to establish an obvious relationship between the symptom and a certain food. For this reason, dietary recommendations are limited and largely based more on experimental approach or pathophysiology knowledge.
IBL International provides a ready solution to help to overcome mentioned difficulties and offers an excellent tool for assessing food intolerance by quantifying the body’s immune response. Food Screen is a state-of-the-art blood test offering a rapid, sensitive and reliable method for detecting specific food-related IgG and IgG4 antibodies.
Advantages of IBL International Food Screen ELISAs
Evaluation of results
|Product||Catalog number||Quantity of plates||Quantity of patients||CE IVD|
|IgG Food Screen 7 ELISA||30131629||15||180||Yes|
|IgG4 Food Screen 7 ELISA||30131628||15||180||Yes|
|IgG Food Screen 24 ELISA||30113481||15||45||Yes|
|IgG4 Food Screen 24 ELISA||30113482||15||45||Yes|
|IgG Food Screen 42 ELISA||30124494||5||10||Yes|
|IgG4 Food Screen 280 ELISA||30115845||15||5||Yes|
The Freedom EVOlyzer® meets the demands of laboratories which process between 4 and 12 plates per run. Combine up to 15 assays per run for better result comparability of entire diagnostic panels.